Marc joined NeuroTrauma in March 2023 and serves as its Chief Medical officer. He brings over 30 years of neuroscience clinical development and regulatory experience, with 11 years in global pharma (Sandoz/Novartis) and 21 years in start-ups and mid-size biotechs. He co-founded three start-ups (Cita NeuroPharmaceuticals, Cervelo Pharmaceuticals, and Adagio/Cynapsus Therapeutics) with the same leadership team, as Chief Medical Officer and Head of R&D, He contributed to all aspects of drug development, and to fundraising, preparation of an IPO and two successful M&A exits (Cita NeuroPharmaceuticals to Vernalis plc; Adagio/Cynapsus Therapeutics to Sunovion Pharmaceuticals). He was instrumental in the search and evaluation of in-licensing opportunities and negotiating partnerships.
He assumed line and project leadership responsibilities from translational medicine to Phase 1-3 development, worldwide regulatory interactions, submissions, and medical affairs, resulting in the successful global marketing of 9 neurology, psychiatry, chronic pain, immunology, endocrinology, and dermatology products (Miacalcin®, Sandimmun Neoral®, Exelon®, Comtan®, Stalevo®, Differin®, Aristada®, Lybalvy®, Kynmobi®). His experience includes small molecules, biologics, and gene therapy development.
In addition to medical oversight, Marc built and directed teams comprising project management, clinical operations, biostatistics, programming, data management, medical writing, and regulatory operations.
Marc’s education includes an MD (Brussels Free University), ScD (Antwerp Tropical Institute), MSc in Biostatistics (joint program of Harvard School of Public Health, Imperial College London, and Leuven Catholic University), MSc Epidemiology and MMD Global Drug Development (Basel University), Master of Public Health (Brussels Free University) and an MBA from Columbia University.
He has a strong interest in statistical modeling and simulation, adaptive trial design, and the integration of pharmacotherapy, artificial intelligence and precision medicine in the diagnosis and treatment of acute and chronic stroke, intracranial hematoma and traumatic brain injury.