TBI occurs when a sudden trauma results in damage to the brain. It is one of the most common causes of disability and death in adults. TBI patients are classified as either mild, moderate or severe, depending on the extent of damage.
There are approximately 4 million TBIs in the U.S. each year. It is estimated that as many as 50% of mild TBIs (concussions) may go unreported.1 Globally, it’s estimated that 69 million people suffer from TBI annually.2
TBI is predicted to remain one of the top three causes of injury-related death and disability up to 2030.3 TBI costs the global economy approximately $400 billion every year through direct and indirect costs.3
NTS-104 will initially be studied in a sub-population of TBI patients having intracranial abnormalities visible on CT imaging, defined as a complicated mild traumatic brain injury (CmTBI).