– Landmark study in mild TBI (mTBI), supported in part by a grant from NeuroTrauma Sciences, helps define CT (computed tomography) scan features associated with adverse outcomes after mTBI –
A head computed tomography (CT) with positive results for acute intracranial hemorrhage is the gold-standard diagnostic biomarker for acute traumatic brain injury (TBI). In moderate to severe TBI, some CT features have been shown to be associated with certain outcomes. In mild TBI, distribution and co-occurrence of pathological CT features and their prognostic importance are not well understood.
In a first-of-its-kind study, TRACK-TBI investigators, under the direction of Geoffrey T. Manley, MD, PhD, Department of Neurological Surgery, University of California, San Francisco, and with external validation from CENTER-TBI, under the direction of Andrew I.R. Maas, MD, PhD and Geoffrey T. Manley, MD, PhD, identified pathological CT features associated with adverse outcomes after mTBI and concluded that pathological features on head computed tomography carried different implications for mild traumatic brain injury prognosis to one year…